May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.
Q: I am wondering which antibody isotypes are present in the Anti-CAV1 monoclonal antibody, clone 8D9. Could you inform me?
A: The isotype of Anti-CAV1 monoclonal antibody, clone 8D9 is IgG2b.
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