General Notes
This product (Catalog No. DPABH-00776) is a rabbit-derived polyclonal antibody raised against human CASP4, targeting the amino acid region 78–265 of the protein. It has been affinity purified by Protein A. Caspase-4 is a human inflammatory cysteine protease encoded by the CASP4 gene on chromosome 11q22.3, functioning primarily in the non-canonical inflammasome pathway to detect cytosolic lipopolysaccharide (LPS) from Gram-negative bacteria and trigger pyroptosis, a form of inflammatory programmed cell death, while also contributing to apoptosis under endoplasmic reticulum (ER) stress conditions.
DPABH-00776 is suitable for use in ELISA (1:4,000–1:8,000), IHC (1:50–1:100), Western blot (WB) (1:1,000–1:4,000) applications.
DPABH-00776 is supplied as a liquid formulation in 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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