Recombinant full length protein corresponding to Human CAPZA2 aa 1-286.Sequence: MADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGA AHAFAQYNLDQFTPVKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDH LRKEATDPRPCEVENAVESWRTSVETALRAYVKEHYPNGVCTVYGKKIDG QQTIIACIESHQFQAKNFWNG
Conjugate
Unconjugated
Applications
Application Notes
IHC-P: 1/50 - 1/200; WB: 1/500 - 1/2000.
Target
Alternative Names
CAPZA2; capping protein (actin filament) muscle Z-line, alpha 2; F-actin-capping protein subunit alpha-2; CAPPA2; CAPZ; F actin capping protein alpha 2 subunit; capZ alpha-2; F-actin capping protein alpha-2 subunit;
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
Pathway
Advanced glycosylation endproduct receptor signaling; Factors involved in megakaryocyte development and platelet production; Hemostasis; Immune System; Innate Immune System;
Citations
Publication ()
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