Anti-CANX monoclonal antibody (DCABH-2821) Knockout Validated

Rabbit anti-Human CANX monoclonal antibody for ICC/IF, WB, IHC-P, ICC, FC

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Clone
FQS4744(3)
Species Reactivity
Rat, Human
Immunogen
A synthetic peptide corresponding to residues near the C terminal of Human Calnexin - ER membrane marker.
Conjugate
Unconjugated

Applications


Application Notes
ICC/IF: 1/200; WB: 1/1000 - 1/5000; IHC-P: 1/100 - 1/4000; Flow Cyt: 1/360.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
CANX; calnexin; CNX; IP90; major histocompatibility complex class I antigen binding protein p88; P90
Entrez Gene ID
UniProt ID

Product Background


Pathway
Adaptive Immune System, organism-specific biosystem; Antigen Presentation: Folding, assembly and peptide loading of class I MHC, organism-specific biosystem; Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Asparagine N-linked glycosylation, organism-specific biosystem; Assembly of Viral Components at the Budding Site, organism-specific biosystem; Calnexin/calreticulin cycle, organism-specific biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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Rabbit IgG Isotype Control CABT-B8382 IA Rabbit PDF Inquiry

References


Gribar, JJ; Ramachandra, M; et al. Functional characterization of glycosylation-deficient human P-glycoprotein using a vaccinia virus expression system. JOURNAL OF MEMBRANE BIOLOGY 173:203-214(2000).
Harris, MR; Yu, YYL; et al. Calreticulin and calnexin interact with different protein and glycan determinants during the assembly of MHC class I. JOURNAL OF IMMUNOLOGY 160:5404-5409(1998).

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