TIMM21 (translocase of inner mitochondrial membrane 21 homolog (yeast)) is a protein-coding gene. Among its related super-pathways are Post-translational protein modification. GO annotations related to this gene include molecular_function. Participates in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of some MITRAC complex, a cytochrome c oxidase (COX) assembly intermediate complex. TIM21 probably shuttles between the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation of early nuclear-encoded subunits into these complexes.
Pathway
Metabolism of proteins; Mitochondrial Protein Import;
Citations
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