Anti-Bacteria C-cadherin Monoclonal antibody (DMAB9444)
Mouse Anti-Bacteria C-cadherin Monoclonal antibody for IP, WB
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C-cadherin fusion protein from cDNA clone for C-cadherin expressed in E.coli.
C-cadherin fusion protein
Cadherins are members of a multigene family of single chain glycoprotein receptors mediating calcium dependent cell-cell adhesion. They play an important role in the growth and development of cells via the mechanisms of control of tissue architecture and the maintenance of tissue integrity. Cadherins are expressed in a tissue specific manner and and are required for assembly of cells into solid tissue. Individual cadherin molecules are known to co-operate with each other to form a linear cell adhesion zipper. In adhesion junctions cadherins are bound to beta and gamma catenins which in turn bind to alpha catenin, an actin binding protein. Cadherins play an important part in tumor invasion and metastasis.
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Kim, YE; Kwon, S; et al. Therapeutic effect of a TM4SF5-specific monoclonal antibody against colon cancer in a mouse model. ONCOTARGET 5:8402-8415(2014).
Nentwig, A; Higgins, RJ; et al. Aberrant E-cadherin, beta-catenin, and glial fibrillary acidic protein (GFAP) expression in canine choroid plexus tumors. JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION 24:14-22(2012).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.