Anti-Bacteria C-cadherin Monoclonal antibody (DMAB9444)

Mouse Anti-Bacteria C-cadherin Monoclonal antibody for IP, WB Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Species Reactivity
Bacteria
Immunogen
C-cadherin fusion protein from cDNA clone for C-cadherin expressed in E.coli.
Conjugate
Unconjugated

Target


Alternative Names
C-cadherin fusion protein

Product Background


Antigen Description
Cadherins are members of a multigene family of single chain glycoprotein receptors mediating calcium dependent cell-cell adhesion. They play an important role in the growth and development of cells via the mechanisms of control of tissue architecture and the maintenance of tissue integrity. Cadherins are expressed in a tissue specific manner and and are required for assembly of cells into solid tissue. Individual cadherin molecules are known to co-operate with each other to form a linear cell adhesion zipper. In adhesion junctions cadherins are bound to beta and gamma catenins which in turn bind to alpha catenin, an actin binding protein. Cadherins play an important part in tumor invasion and metastasis.

Citations


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References


Anz, D; Mueller, W; et al. CD103 is a hallmark of tumor-infiltrating regulatory T cells. INTERNATIONAL JOURNAL OF CANCER 129:2417-2426(2011).
Davidov, T; Nagar, M; et al. Carbonic anhydrase 4 and crystallin alpha-B immunoreactivity may distinguish benign from malignant thyroid nodules in patients with indeterminate thyroid cytology. JOURNAL OF SURGICAL RESEARCH 190:565-574(2014).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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