Anti-BTK monoclonal antibody (CAB-8425MH)

Mouse anti-Human BTK monoclonal antibody for WB, FC, IHC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
15G8
Species Reactivity
Human
Immunogen
Full length human recombinant protein of human BTK (NP_000052) produced in HEK293T cell
Conjugate
Unconjugated

Applications


Application Notes
WB: 1:2000; IHC: 1:50; IF: 1:100; FLOW: 1:100
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
BTK; Bruton agammaglobulinemia tyrosine kinase; AGMX1, IMD1; tyrosine-protein kinase BTK; ATK; PSCTK1
Entrez Gene ID
UniProt ID

Product Background


Pathway
Adaptive Immune System, organism-specific biosystem; Antigen Activates B Cell Receptor Leading to Generation of Second Messengers, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; B cell receptor signaling pathway, organism-specific biosystem; B cell receptor signaling pathway, conserved biosystem; BCR signaling pathway, organism-specific biosystem; Class I PI3K signaling events, organism-specific biosystem;

Citations


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References


Wollscheid, B; Reth, M; et al. Characterization of the B cell-specific adaptor SLP-65 and other protein tyrosine kinase substrates by two-dimensional gel electrophoresis. IMMUNOLOGY LETTERS 68:95-99(1999).
Yu, L; Mohamed, AJ; et al. Regulation of Bruton tyrosine kinase by the peptidylprolyl isomerase Pin1. JOURNAL OF BIOLOGICAL CHEMISTRY 281:18201-18207(2006).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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