Specifications
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human BACH1/BRIP1 aa 400-500. The exact sequence is proprietary.Database link: Q9BX63
Applications
Application Notes
WB: 1/1000 - 1/5000;
Target
Alternative Names
BRIP1; BRCA1 interacting protein C-terminal helicase 1; Fanconi anemia group J protein; BACH1; BRCA1/BRCA2 associated helicase 1; FANCJ; OF; ATP-dependent RNA helicase BRIP1; BRCA1/BRCA2-associated helicase 1; BRCA1-associated C-terminal helicase 1; BRCA1
Product Background
Antigen Description
DNA-dependent ATPase and 5 to 3 DNA helicase required for the maintenance of chromosomal stability. Acts late in the Fanconi anemia pathway, after FANCD2 ubiquitination. Involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1.
Pathway
DNA Repair, organism-specific biosystem; Double-Strand Break Repair, organism-specific biosystem; Fanconi anemia pathway, organism-specific biosystem; Fanconi anemia pathway, conserved biosystem; Homologous DNA pairing and strand exchange, organism-specific biosystem; Homologous Recombination Repair, organism-specific biosystem; Homologous recombination repair of replication-independent double-strand breaks, organism-specific biosystem;
Citations
Publication ()
Have you cited DCABH-6952 in a publication?
Let us know and earn a reward for your research.
COA
Loading ......
