Anti-BPHL monoclonal antibody (DCABH-10760) Made to order

Rabbit anti-Human BPHL monoclonal antibody for WB, ELISA

View other BPHL antibodies

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
A synthetic peptide of human BPHL is used for rabbit immunization.
Conjugate
Unconjugated

Target


Alternative Names
BPHL; biphenyl hydrolase-like (serine hydrolase); MCNAA; valacyclovir hydrolase; Bph rp; breast epithelial mucin associated antigen
Entrez Gene ID
UniProt ID

Product Background


Gene summary
BPHL (Biphenyl Hydrolase-Like (Serine Hydrolase)) is a Protein Coding gene. Among its related pathways are Metabolism and cytochrome P450. GO annotations related to this gene include hydrolase activity. This gene encodes a member of the serine protease family of hydrolytic enzymes which contain a serine in their active site. The encoded protein may play a role in activation of the antiviral prodrug valacyclovir. Alternatively spliced transcript variants have been described.
Antigen Description
This gene encodes a member of the serine protease family of hydrolytic enzymes which contain a serine in their active site. The encoded protein may play a role in activation of the antiviral prodrug valacyclovir. Alternatively spliced transcript variants have been describedSerine hydrolase that catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir and valganciclovir. Activates valacyclovir to acyclovir. May play a role in detoxification processes. It is a specific alpha-amino acid ester hydrolase that prefers small, hydrophobic, and aromatic side chains and does not have a stringent requirement for the leaving group other than preferring a primary alcohol. The function about BPHL antigen include hydrolase activity.

Citations


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We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Kim, I; Chu, XY; et al. Identification of a human valacyclovirase - Biphenyl hydrolase-like protein as valacyclovir hydrolase. JOURNAL OF BIOLOGICAL CHEMISTRY 278:25348-25356(2003).
Kim, I; Song, XQ; et al. A novel nucleoside prodrug-activating enzyme: Substrate specificity of biphenyl hydrolase-like protein. MOLECULAR PHARMACEUTICS 1:117-127(2004).

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