Anti-BNC1 monoclonal antibody (DCABH-10753) Made to order

Rabbit anti-Human BNC1 monoclonal antibody for WB, ELISA

View other BNC1 antibodies

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
A synthetic peptide of human BNC1 is used for rabbit immunization.
Conjugate
Unconjugated

Target


Alternative Names
BNC1; basonuclin 1; basonuclin , BNC; zinc finger protein basonuclin-1; HsT19447; zinc finger protein basonuclin
Entrez Gene ID
UniProt ID

Product Background


Gene summary
BNC1 (Basonuclin 1) is a Protein Coding gene. Diseases associated with BNC1 include subdural empyema. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is BNC2. The protein encoded by this gene is a zinc finger protein present in the basal cell layer of the epidermis and in hair follicles. It is also found in abundance in the germ cells of testis and ovary. This protein is thought to play a regulatory role in keratinocyte proliferation and it may also be a regulator for rRNA transcription. Alternative splicing of this gene results in multiple transcript variants, and multiple polyadenylation sites are indicated.
Antigen Description
The protein encoded by this gene is a zinc finger protein present in the basal cell layer of the epidermis and in hair follicles. It is also found in abundance in the germ cells of testis and ovary. This protein is thought to play a regulatory role in keratinocyte proliferation and it may also be a regulator for rRNA transcription. This gene seems to have multiple alternatively spliced transcript variants, but their full-length nature is not known yet. There seems to be evidence of multiple polyadenylation sites for this gene. Likely to be a transcription factor specific for squamous epithelium and for the constituent keratinocytes at a stage either prior to or at the very beginning of terminal differentiation. May play a role in the differentiation of spermatozoa and oocytes. Zinc finger protein basonuclin-1 is a protein that in humans is encoded by the BNC1 gene. 0The function about BNC1 antigen include DNA binding; metal ion binding; sequence-specific DNA binding transcription factor activity; zinc ion binding.

Citations


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We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Smyth, IM; Wilming, L; et al. Genomic anatomy of the Tyrp1 (brown) deletion complex. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 103:3704-3709(2006).
Dunwell, TL; Hesson, LB; et al. Epigenetic analysis of childhood acute lymphoblastic leukemia. EPIGENETICS 4:185-193(2009).

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