Anti-BDH1 monoclonal antibody, clone 5C4

Antibody Isotype

IgG2a

Clone

5C4

Species Reactivity

Human; Mouse

Immunogen

BDH1 (AAH11964, 1 a.a. ~ 343 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Conjugate

Alternative Names

BDH1; 3-hydroxybutyrate dehydrogenase, type 1; 3 hydroxybutyrate dehydrogenase (heart, mitochondrial) , BDH; D-beta-hydroxybutyrate dehydrogenase, mitochondrial; SDR9C1; short chain dehydrogenase/reductase family 9C; member 1; (R)-3-hydroxybutyrate dehydr

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described.

Pathway

Butanoate metabolism, organism-specific biosystem; Butanoate metabolism, conserved biosystem; FOXA2 and FOXA3 transcription factor networks, organism-specific biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Ketone body metabolism, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem.