Anti-BAIAP2 monoclonal antibody, clone 2048DU26.2.4

Antibody Isotype

IgG2b

Clone

2048DU26.2.4

Species Reactivity

Human; Mouse

Conjugate

Application Notes

WB: 1:1000

Alternative Names

BAIAP2; Brain-specific angiogenesis inhibitor 1-associated protein 2; Brain-specific angiogenesis inhibitor 1-associated protein 2; Fas ligand-associated factor 3; Brain-specific angiogenesis inhibitor 1-associated protein 2; Insulin receptor substrat

Entrez Gene ID

UniProt ID

Antigen Description

Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection.

Pathway

Adherens junction; CDC42 signaling events; ErbB1 downstream signaling; Fcgamma receptor (FCGR) dependent phagocytosis; Immune System; Innate Immune System; RAC1 signaling pathway; Regulation of Actin Cytoskeleton;