Anti-ARG2 (aa 289-338) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Synthetic peptide from within the C termina amino acids 289-338 (SALDLVEVNP QLATSEEEAK TTANLAVDVI ASSFGQTREG GHIVYDQLPT) of Human Arg2 (NP_001163)

Conjugate

Application Notes

WB: 1 μg/ml.

Alternative Names

ARG2; arginase, type II; arginase-2, mitochondrial; arginase 2; kidney arginase; type II arginase; nonhepatic arginase; kidney-type arginase; non-hepatic arginase; L-arginine ureahydrolase; L-arginine amidinohydrolase;

Entrez Gene ID

UniProt ID

Antigen Description

May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders.

Pathway

Amoebiasis; Arginine and proline metabolism; Metabolic pathways; Metabolism; Metabolism of amino acids and derivatives;