Anti-ARG2 monoclonal antibody, clone FQS0584

Antibody Isotype

IgG

Clone

FQS0584

Species Reactivity

Human

Immunogen

A synthetic peptide corresponding to residues at the C terminus of Human Arg2.

Conjugate

Application Notes

ICC/IF: 1/250 - 1/500; Flow Cyt: 1/100 - 1/10000; WB: 1/1000 - 1/10000.

Alternative Names

ARG2; arginase, type II; arginase-2, mitochondrial; arginase 2; kidney arginase; type II arginase; nonhepatic arginase; kidney-type arginase; non-hepatic arginase; L-arginine ureahydrolase; L-arginine amidinohydrolase;

Entrez Gene ID

UniProt ID

Antigen Description

May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders.

Pathway

Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem;