Rabbit Anti-Human AVPR2 (a.a. 1-83) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Recombinant human AVPR2 protein; Source: E. coli derived, PET28a; Tag: 6*His; Domain: 1-83 aa of BC112181

Conjugate

Application Notes

WB: 1:1000-1:4000

General Notes

This product (Catalog No. DPABH-25675) is a rabbit-derived polyclonal antibody raised against human AVPR2, targeting the amino acid region 1–83 of the protein. It has been affinity purified by Protein A. AVPR2 is a Gs-coupled vasopressin receptor essential for renal water reabsorption, acting through cAMP-PKA-dependent trafficking of aquaporin-2. Localized to principal cells of the collecting duct, AVPR2 integrates hormonal cues to maintain osmotic and fluid homeostasis. Mutations lead to X-linked nephrogenic diabetes insipidus, while rare activating variants cause SIADH. Because of its central role in renal physiology and clear clinical associations, AVPR2 is a key target in water-balance disorders and pharmacologic modulation of diuresis.
DPABH-25675 is suitable for use in Western blot (WB) (1:1,000–1:4,000) application.
DPABH-25675 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

ADHR; Antidiuretic hormone receptor; AVPR V2; DI1; DIR

Entrez Gene ID

UniProt ID