Anti-ATP6AP1 (aa 51-150) polyclonal antibody

Species Reactivity

Human

Immunogen

ATP6AP1 (NP_001174, 51 a.a. ~ 150 a.a) partial recombinant protein with GST tag. The sequence is SSDRDLWAPAADTHEGHITSDLQLSTYLDPALELGPRNVLLFLQDKLSIEDFTAYGGVFG NKQDSAFSNLENALDLAPSSLVLPAVDWYAVSTLTTYLQE

Conjugate

Alternative Names

ATP6AP1; ATPase, H+ transporting, lysosomal accessory protein 1; 16A; CF2; Ac45; XAP3; XAP-3; ATP6S1; VATPS1; ATP6IP1; V-type proton ATPase subunit S1; protein XAP-3; H-ATPase subunit; V-ATPase subunit S1; V-ATPase Ac45 subunit; V-ATPase S1 accessory prot

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a component of a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules. This protein may also play a role in early development.

Pathway

Epithelial cell signaling in Helicobacter pylori infection; Hepatitis B; Lysosome; Oxidative phosphorylation.