This product (Catalog No. DPABH-12188) is a rabbit-derived polyclonal antibody raised against human ATMIN. This antibody exhibits cross-reactivity with ATMIN from mouse. It has been affinity purified by Protein A. ATM interactor (ATMIN), also known as ASCIZ (ATM/ATR-Substrate Chk2-Interacting Zn2+-finger protein), is a critical regulator of the ATM kinase signaling pathway, particularly in response to oxidative stress and changes in chromatin structure rather than direct DNA double-strand breaks (DSBs). It acts as a cofactor that binds to and stabilizes ATM, protecting cells from premature senescence. DPABH-12188 is suitable for use in Western blot (WB) (1:500–1:2,000) application. DPABH-12188 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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