Synthetic Human ATMIN blocking peptide for BL
Ubiquitously expressed in normal tissues and cancer cell lines with highest levels in placenta and skeletal muscle.
Contains 2 C2H2-type zinc fingers.
Nucleus. Nuclear, in discrete foci during G1 phase.
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.
Plays a crucial role in cell survival and RAD51 foci formation in response to methylating DNA damage. Involved in regulating the activity of ATM in the absence of DNA damage. May play a role in stabilizing ATM.
dynein binding; metal ion binding; protein binding; transcription regulatory region DNA binding;
ATMIN; ATM interactor; ASCIZ; ZNF822; ATM INteracting protein; zinc finger protein 822; ATM/ATR-Substrate Chk2-Interacting Zn++-finger protein; ATM/ATR-substrate CHK2-interacting zinc finger protein; ATM/ATR-substrate CHEK2-interacting zinc finger protein;