Anti-ASAP1 (aa 1030-1129) polyclonal antibody

Species Reactivity

Human

Immunogen

DDEF1 (NP_060952, 1030 a.a. ~ 1129 a.a) partial recombinant protein with GST tag. The sequence is VQSRDAIQKQASEDSNDLTPTLPETPVPLPRKINTGKNKVRRVKTIYDCQADNDDELTFI EGEVIIVTGEEDQEWWIGHIEGQPERKGVFPVSFVHILSD

Conjugate

Alternative Names

ASAP1; ArfGAP with SH3 domain, ankyrin repeat and PH domain 1; PAP; PAG2; AMAP1; DDEF1; ZG14P; CENTB4; arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1; DEF-1; centaurin, beta 4; PIP2-dependent ARF1 GAP; ARF GTPase-activating protein

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes an ADP-ribosylation factor (ARF) GTPase-activating protein. The GTPase-activating activity is stimulated by phosphatidylinositol 4,5-biphosphate (PIP2), and is greater towards ARF1 and ARF5, and lesser for ARF6. This gene maybe involved in regulation of membrane trafficking and cytoskeleton remodeling. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Pathway

Arf1 pathway; Endocytosis; Signaling events mediated by focal adhesion kinase;