Anti-ARHGEF16 monoclonal antibody, clone FQS0061

Name: Anti-ARHGEF16 monoclonal antibody, clone FQS0061
SKU: DCABH-4347
Rating: 5 (1 reviews)

Rabbit anti-Human ARHGEF16 monoclonal antibody for WB, IHC-P, ICC/IF, FC

Write a review

COA

SDS

Datasheet

Summary

Specifications

Antibody Isotype

IgG

Clone

FQS0061

Species Reactivity

Mouse; Human

Immunogen

Synthetic peptide corresponding to residues in Human Rho guanine exchange factor 16 (UniProt Q5VV41).

Conjugate

Unconjugated

Applications

Application Notes

WB: 1/1000 - 1/10000; IHC-P: 1/50 - 1/100; ICC/IF: 1/100 - 1/250; Flow Cyt: 1/10 - 1/100;

Target

Alternative Names

ARHGEF16; Rho guanine nucleotide exchange factor (GEF) 16; rho guanine nucleotide exchange factor 16; GEF16; NBR; putative neuroblastoma protein; ephexin-4; Rho guanine exchange factor (GEF) 16;

Entrez Gene ID

27237

UniProt ID

B3KTS4

Product Background

Antigen Description

Guanyl-nucleotide exchange factor of the RHOG GTPase stimulating the exchange of RHOG-associated GDP for GTP. May play a role in chemotactic cell migration by mediating the activation of RAC1 by EPHA2. May also activate CDC42 and mediate activation of CDC42 by the viral protein HPV16 E6.

Pathway

Cell death signalling via NRAGE, NRIF and NADE, organism-specific biosystem; G alpha (12/13) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; NRAGE signals death through JNK, organism-specific biosystem; Rho GTPase cycle, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by GPCR, organism-specific biosystem.

Citations