Anti-APOA4 (full length) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Recombinant full length protein, corresponding to amino acids 1-396 of Human APOA4 (AAH74764.1).

Conjugate

Application Notes

WB: 1/500 - 1/2500; IHC-P: 3 μg/ml.

Alternative Names

APOA4; apolipoprotein A-IV; apo-AIV; apoA-IV; apolipoprotein A4; MGC142154; MGC142156;

Entrez Gene ID

Antigen Description

APOA4 (apolipoprotein A-IV) is a component of HDL and chylomicrons. Its primary site of synthesis is the intestine, in association with lymph chylomicron particles. Although its precise function is not known, APOA4 is a potent activator of lecithin-cholesterol acyltransferase (LCAT) in vitro. In rodents, Apo A-IV inhibits gastric emptying and serves as a satiety factor whose synthesis and secretion are increased by the ingestion of dietary fat. It also possesses anti-inflammatory and antiatherogenic properties

Pathway

Amyloids; Chylomicron-mediated lipid transport; Disease; Fat digestion and absorption; Lipid digestion, mobilization, and transport; Lipoprotein metabolism;