General Notes
This product (Catalog No. DPABH-28593) is a rabbit-derived polyclonal antibody raised against human AP1G1, targeting the amino acid region 1–577 of the protein. It has been affinity purified by Protein A. AP1G1 (AP-1 complex subunit gamma-1) encodes a component of the adaptor protein complex 1 (AP-1), which is involved in clathrin-mediated vesicular trafficking between the trans-Golgi network and endosomes. AP1G1 is a large structural subunit of the AP-1 heterotetramer and contributes to cargo protein sorting by recognizing sorting signals on transmembrane proteins and facilitating their incorporation into clathrin-coated vesicles. Through its role in intracellular membrane transport, AP1G1 participates in protein maturation, receptor recycling, and lysosomal targeting pathways. Dysregulation of AP1G1 expression or function may affect cellular trafficking homeostasis and has been studied in the context of neurological disorders and cancer biology.
DPABH-28593 is suitable for use in ELISA (1:4,000–1:8,000), IHC (1:50–1:100), Western blot (WB) (1:1,000–1:4,000) applications.
DPABH-28593 is supplied as a liquid formulation in 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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