Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Synthetic peptide corresponding to C terminal residues in Human gamma Adaptin (UniProt O43747).
Applications
Application Notes
WB: 1/1000 - 1/10000; IHC-P: 1/50 - 1/100;
Target
Alternative Names
AP1G1; adaptor-related protein complex 1, gamma 1 subunit; ADTG, CLAPG1; AP-1 complex subunit gamma-1; gamma1 adaptin; gamma adaptin; gamma1-adaptin; golgi adaptor HA1/AP1 adaptin gamma subunit; adaptor protein complex AP-1 subunit gamma-1; golgi adaptor
Product Background
Antigen Description
Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
Pathway
Clathrin derived vesicle budding, organism-specific biosystem; Disease, organism-specific biosystem; Golgi Associated Vesicle Biogenesis, organism-specific biosystem; HIV Infection, organism-specific biosystem; Host Interactions of HIV factors, organism-specific biosystem; Lysosome, organism-specific biosystem; Lysosome, conserved biosystem;
Citations
Publication ()
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