Anti-AP2B1 monoclonal antibody, clone 211/2

Antibody Isotype

IgG1

Clone

211/2

Species Reactivity

Bovine

Immunogen

AP2 adaptor from bovine brain.

Conjugate

Alternative Names

AP2B1; adaptor-related protein complex 2, beta 1 subunit; AP-2 complex subunit beta; AP105B; beta1-adaptin; beta2-adaptin; beta-1-adaptin; beta-2-adaptin; beta-adaptin 1; AP-1 complex subunit beta-1; adaptor protein complex AP-2 subunit beta; golgi adapto

Entrez Gene ID

UniProt ID

Antigen Description

Subunit of clathrin associated adaptor protein complex 1 that plays a role in protein sorting in the late Golgi/trans Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Adaptor protein complex 1 (AP1) is an heterotetramer composed of two large adaptins (gamma type subunit AP1G1 and beta type subunit AP1B1), a medium adaptin (mu type subunit AP1M1 or AP1M2) and a small adaptin (sigma type subunit AP1S1 or AP1S2 or AP1S3).

Pathway

Endocrine and other factor-regulated calcium reabsorption, organism-specific biosystem; Endocrine and other factor-regulated calcium reabsorption, conserved biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Huntingtons disease, organism-specific biosystem; Huntingtons disease, conserved biosystem; Synaptic vesicle cycle, organism-specific biosystem;