Specifications
Species Reactivity
Human; Mouse
Immunogen
Synthetic peptide corresponding to residues near the C terminal of human acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
Applications
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:200
General Notes
This product (Catalog No. DPABH-16701) is a rabbit-derived polyclonal antibody raised against human ANP32E. This antibody exhibits cross-reactivity with ANP32E from mouse. It has been affinity purified by Protein A. Acidic leucine-rich nuclear phosphoprotein 32 family member E is a protein that in humans is encoded by the ANP32E gene. The ANP32E gene is located on chromosome 1q22. In mammalian cells, ANP32E has been shown to be an H2A.Z chaperone capable of promoting the removal of H2A.Z from chromatin. In brain tissue, ANP32E together with Cpd1 regulate protein phosphatase 2A activity at synapses during synaptogenesis and has been observed to form a complex with ANP32A and SET that stabilizes short-lived mRNAs containing AU-rich elements, as well as having acetyltransferase inhibitory activity (in a complex with SET) and having a role in chromatin remodeling and transcriptional regulation.
DPABH-16701 is suitable for use in Western blot (WB) (1:500–1:2,000), IHC (1:50–1:200) applications.
DPABH-16701 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Target
Alternative Names
Acidic (leucine rich) nuclear phosphoprotein 32 family member E; Acidic leucine-rich nuclear phosphoprotein 32 family member E; AN32E_HUMAN; ANP32E; Cerebellar postnatal development protein 1; LANP like protein; LANP-L; LANP-like protein; LANPL; Leucine rich acidic nuclear protein like; MGC5350
Citations
Publication ()
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