This gene encodes an important intermediate enzyme in polyamine biosynthesis. The polyamines spermine, spermidine, and putrescine are low-molecular-weight aliphatic amines essential for cellular proliferation and tumor promotion. Two alternatively spliced transcript variants that encode different proteins have been identified.
Pathway
Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; Cysteine and methionine metabolism, organism-specific biosystem; Cysteine and methionine metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem;
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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Echevarria-Machado, I; Ku-Gonzalez, A; et al. Interaction of spermine with a signal transduction pathway involving phospholipase C, during the growth of Catharanthus roseus transformed roots. PHYSIOLOGIA PLANTARUM 120:140-151(2004).
Tian, H; Liu, XX; et al. Adenovirus-mediated expression of both antisense ornithine decarboxylase (ODC) and sadenosylmethionine decarboxylase (AdoMetDC) inhibits human esophageal squamous carcinoma cell growth. GENE THERAPY AND MOLECULAR BIOLOGY 11B:151-159(2007).
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COA
Certificate of Analysis
