ALG6 (NP_037471, 25 a.a. ~ 114 a.a) partial recombinant protein with GST tag. The sequence is SYSGAGKPPMFGDYEAQRHWQEITFNLPVKQWYFNSSDNNLQYWGLDYPPLTAYHSLLCA YVAKFINPDWIALHTSRGYESQAHKLFMRT
This gene encodes a member of the ALG6/ALG8 glucosyltransferase family. The encoded protein catalyzes the addition of the first glucose residue to the growing lipid-linked oligosaccharide precursor of N-linked glycosylation. Mutations in this gene are associated with congenital disorders of glycosylation type Ic.
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