Recombinant human ALG3 protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 1-199 aa of BC002839
Conjugate
Unconjugated
Applications
Application Notes
WB: 1:500-1:2000 IHC: 1:50-1:500
General Notes
This product (Catalog No. DPABH-03342) is a rabbit-derived polyclonal antibody raised against human ALG3, targeting the amino acid region 1–199 of the protein. This antibody exhibits cross-reactivity with Human ALG3 from mouse. It has been affinity purified by Protein A. Alpha-1,3-mannosyltransferase (ALG3) encodes an endoplasmic reticulum-localized ALG3 family member that participates in N-glycan synthesis. ALG3 contributes to high mannose-type N-glycans in several cancers, and mannose-type N-glycan upregulation has been shown to be related to cancer progression. ALG3 is overexpressed in oral squamous cell carcinoma(PMID: 33084111), non-small cell lung cancer(PMID: 31899049), and breast cancer(PMID: 33931075) and hepatocellular carcinoma(PMID: 35782861). DPABH-03342 is suitable for use in Western blot (WB) (1:500–1:2,000), IHC (1:50–1:500) applications. DPABH-03342 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Target
Alternative Names
ALG3; CDGS4; D16Ertd36e; NOT; Not56; Not56 like protein; NOT56L
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