Fusion protein corresponding to residues near the C terminal of human aldehyde dehydrogenase 6 family, member A1
Conjugate
Unconjugated
Applications
Application Notes
WB: 1:500-1:2000 IHC: 1:50-1:200
General Notes
This product (Catalog No. DPABH-18974) is a rabbit-derived IgG polyclonal antibody raised against human ALDH6A1. It has been affinity purified by protein A. This gene encodes a member of the aldehyde dehydrogenase protein family. The encoded protein is a mitochondrial methylmalonate semialdehyde dehydrogenase that plays a role in the valine and pyrimidine catabolic pathways. This protein catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. Alternate splicing results in multiple transcript variants. DPABH-18974 is suitable for use in Western blot (WB) (1:500–1:2,000), IHC (1:50–1:200) applications. DPABH-18974 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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