Rabbit Anti-Human ALDH1A2 (a.a. 181-481) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse; Rat

Immunogen

Recombinant human ALDH1A2 protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 181-481 aa of BC030589

Conjugate

Application Notes

WB: 1:5000-1:50000
IP: 0.5-4.0 μg for 1.0-3.0 mg of total protein lysate
IHC: 1:200-1:800
IF/ICC: 1:150-1:600

General Notes

This product (Catalog No. DPABH-02640) is a rabbit-derived polyclonal antibody raised against human ALDH1A2, targeting the amino acid region 181–481 of the protein. This antibody exhibits cross-reactivity with Human ALDH1A2 from mouse and rat. It has been affinity purified by Protein A. ALDH1A2(aldehyde dehydrogenase family 1 member A2) is also named as RALDH2(retinal dehydrogenase 2) and belongs to the aldehyde dehydrogenase family. It is a cytosolic homotetramer(56.7 kDa subunits) exhibiting complex expression patterns throughout embryonic development. ALDH1A2 plays a role in retinoid metabolism during embryonic development where it is considered to be the major retinoic acid-synthesizing enzyme during early embryogenesis(PMID:20735668). Its expression is reduced in primary prostate tumors compared with normal prostate tissue suggested that it is normally expressed in the epithelial compartment of prostate tissue(PMID:16166285).It has 2 isoforms produced by alternative splicing.
DPABH-02640 is suitable for use in Western blot (WB) (1:5,000–1:50,000), IP (0.5-4.0 μg for 1.0-3.0 mg of total protein lysate), IHC (1:200–1:800), IF/ICC (1:150–1:600) applications.
DPABH-02640 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

ALDH1A 2; EC:1.2.1.36; RALDH 2; RALDH(II); RalDH2

Entrez Gene ID

UniProt ID