Rabbit Anti-Human AKR7A2 (a.a. 81-150) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Mouse; Human; Rat

Immunogen

KLH conjugated synthetic peptide derived from human AKR7A2: 81-150/359

Conjugate

Application Notes

WB: 1:500-2000

General Notes

This product (Catalog No. DPABH-19727) is a rabbit-derived IgG polyclonal antibody raised against human AKR7A2, targeting the amino acid region 81–150 of the protein. This antibody exhibits cross-reactivity with AKR7A2 from mouse and rat. It has been affinity purified by Protein A. The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. Alternative splicing results in multiple transcript variants.
DPABH-19727 is suitable for use in Western blot (WB) (1:500–1:2,000) application.
DPABH-19727 is supplied as a liquid formulation in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

AFAR; AFAR1; AFB1 aldehyde reductase 1; AFB1 AR1; AFB1-AR 1; AFB1AR1; Aflatoxin aldehyde reductase; Aflatoxin B1 aldehyde reductase member 2; Aflatoxin beta1 aldehyde reductase; Aiar; AKR7; Akr7a2; Aldo keto reductase family 7; Aldo keto reductase family 7 member A2 aflatoxin aldehyde reductase; Aldo keto reductase family 7 member A2; Aldoketoreductase 7; ARK72_HUMAN; SSA reductase; SSA reductase; Succinic semialdehyde reductase

Entrez Gene ID

UniProt ID