Anti-Alpha fetoprotein monoclonal antibody, clone FQ2127Z

In an age in which content is indexed by Internet search tools, transnational new agencies and traditional news media are still important sources of information for data bases in the main languages, according to their own criteria of relevance on what and how to inform. With the purpose of mapping the political classifications adopted on the coverage of the 2010 Brazilian presidential election, this article analyses terms used before, after or as a substitution to the name of the four main candidates Dilma Rousseff (PT), Jose Serra (PSDB), Marina Silva, and Plinio de Arruda Sampaio (PSOL) -, present in 261 news texts, both in English and Spanish, of four agencies (AFP, AP, EFE and Reuters) and four traditional news media (BBC and CNN TV networks, plus the newspapers El Pais and The New York Times). From these results, parallels are traced among the criteria adopted by the journalistic sources when attributing relevance to information associated to each candidate and the generalizations of Tefko Saracevic (2009) about how information system's users infer relevance in search processing, suggested based on 40 years of studies in the field of Information Science.

Beckwith-Wiedemann syndrome (BWS) is an overgrowth syndrome, caused by alterations in a cluster of imprinted genes located within the chromosome region 11p15.5. Common clinical features are overgrowth, macroglossia, lateralized overgrowth, abdominal wall defects, neonatal hypoglycemia and an increased risk of embryonal tumors, such as hepatoblastomas. Periodic screening for abdominal tumors is recommended. Vascular tumors are uncommon in BWS. Diffuse infantile hepatic hemangiomas (DIHHs) are rare vascular tumors with potentially lethal complications, in particular acquired consumptive hypothyroidism, high-output cardiac failure, liver failure and abdominal compartment syndrome. We describe a 2-month-old patient with hallmark clinical features of BWS and confirmed a genetic diagnosis with mosaic paternal uniparental disomy of chromosome 11p15.5 (UPD[11]pat). The patient developed hepatomegaly and elevated alpha-fetoprotein (AFP) and was therefore suspected of having a hepatoblastoma. Abdominal echo-color Doppler and a CT-scan allowed diagnosis of DIHHs. She was closely monitored and underwent treatment with propranolol. Oral propranolol was effective in reducing hepatic lesions without side effects. This report may suggest that vascular tumors can also be associated with BWS.