Anti-ADCK3 (aa 1-100) polyclonal antibody

Species Reactivity

Human

Immunogen

CABC1 (AAH05171, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. The sequence is MAAILGDTIMVAKGLVKLTQAAVETHLQHLGIGGELIMAARALQSTAVEQIGMFLGKVQG QDKHEEYFAENFGGPEGEFHFSVPHAAGASTDFSSASAPD

Conjugate

Alternative Names

ADCK3; aarF domain containing kinase 3; COQ8; ARCA2; CABC1; SCAR9; COQ10D4; chaperone activity of bc1 complex-like, mitochondrial; coenzyme Q8 homolog; aarF domain-containing protein kinase 3; chaperone, ABC1 activity of bc1 complex homolog;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found; however, their full-length nature has not been determined.