Synthetic peptide corresponding to Human ADAMTS5 aa 529-541.Sequence: CLTKKLPAVEGTP Database link: Q9UNA0
Conjugate
Unconjugated
Applications
Application Notes
IHC-P: 1/10 - 1/50; WB: 1/500 - 1/2000.
Target
Alternative Names
ADAMTS5; ADAM metallopeptidase with thrombospondin type 1 motif, 5; a disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase 2); A disintegrin and metalloproteinase with thrombospondin motifs 5; ADAMTS11; A
Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. May play a role in proteolytic processing mostly during the peri-implantation period.
Pathway
Endochondral Ossification;
Citations
Publication ()
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COA
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