ACADVL (NP_000009, 345 a.a. ~ 434 a.a) partial recombinant protein with GST tag. The sequence is AAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANM DQGATDFQIEAAISKIFGSEAAWKVTDECI
Conjugate
Unconjugated
Target
Alternative Names
ACADVL; acyl-CoA dehydrogenase, very long chain; ACAD6; LCACD; VLCAD; very long-chain specific acyl-CoA dehydrogenase, mitochondrial; acyl-Coenzyme A dehydrogenase, very long chain;
The protein encoded by this gene is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. This acyl-Coenzyme A dehydrogenase is specific to long-chain and very-long-chain fatty acids. A deficiency in this gene product reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy. Alternative splicing results in multiple transcript variants encoding different isoforms.
Pathway
Beta oxidation of palmitoyl-CoA to myristoyl-CoA; Fatty Acid Beta Oxidation; Fatty acid degradation; Fatty acid metabolism
Citations
Publication ()
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COA
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