Recombinant human ABR protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 1-87 aa of NM_021962
Conjugate
Unconjugated
Applications
Application Notes
WB: 1:1000-1:4000 IHC: 1:500-1:2000
General Notes
This product (Catalog No. DPABH-00575) is a rabbit-derived polyclonal antibody raised against human ABR, targeting the amino acid region 1–87 of the protein. This antibody exhibits cross-reactivity with Human ABR from mouse and rat. It has been affinity purified by Protein A. ABR (Active breakpoint cluster region-related protein) is the only protein known in humans and mice to share high homology with BCR (68% amino acid identity). BCR(Breakpoint cluster region) gene was originally identified due to its involvement in a specific chromosomal translocation that causes the development of chronic myeloid leukemia and a subset of acute lymphoblastic leukemia. The C-terminus is a GTPase-activating protein domain which stimulates GTP hydrolysis by RAC1, RAC2 and CDC42. (PMID: 17116687, PMID: 37507586). DPABH-00575 is suitable for use in Western blot (WB) (1:1,000–1:4,000), IHC (1:500–1:2,000) applications. DPABH-00575 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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