Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Synthetic peptide corresponding to C-terminal residues of Human ABR (UniProt: Q12979)
Applications
Application Notes
WB: 1/1000 - 1/10000; IP: 1/10 - 1/100; Flow Cyt: 1/100 - 1/500;
Target
Alternative Names
ABR; active BCR-related; active BCR related gene; active breakpoint cluster region-related protein; MDB; FLJ45954;
Product Background
Antigen Description
GTPase-activating protein for RAC and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them.
Pathway
Cell death signalling via NRAGE, NRIF and NADE, organism-specific biosystem; G alpha (12/13) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; NRAGE signals death through JNK, organism-specific biosystem; Regulation of RAC1 activity, organism-specific biosystem; Regulation of RhoA activity, organism-specific biosystem; Rho GTPase cycle, organism-specific biosystem;
Citations
Publication ()
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COA
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