Anti-ABCB1 monoclonal antibody, clone FQS21475 Knockout Validated

Name: Anti-ABCB1 monoclonal antibody, clone FQS21475
SKU: DCABH-5160
Rating: 5 (1 reviews)

Rabbit anti-Human ABCB1 monoclonal antibody for WB, IHC-P

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COA

SDS

Datasheet

Summary

Specifications

Antibody Isotype

IgG

Clone

FQS21475

Species Reactivity

Human

Immunogen

Recombinant fragment corresponding to residues in Human P Glycoprotein (P08183).

Conjugate

Unconjugated

Applications

Application Notes

WB: 1/1000 - 1/5000; IHC-P: 1/50 - 1/100;

Target

Alternative Names

ABCB1; ATP-binding cassette, sub-family B (MDR/TAP), member 1; CLCS, colchicin sensitivity , MDR1, PGY1; multidrug resistance protein 1; ABC20; CD243; GP170; P gp; P-glycoprotein 1; colchicin sensitivity; doxorubicin resistance; CLCS; MDR1; P-GP; PGY1;

Entrez Gene ID

5243

UniProt ID

A4D1D2

Product Background

Antigen Description

Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.

Pathway

ABC transporters, organism-specific biosystem; ABC transporters, conserved biosystem; ABC-family proteins mediated transport, organism-specific biosystem; Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Codeine and morphine metabolism, organism-specific biosystem; HIF-1-alpha transcription factor network, organism-specific biosystem;

Citations