Anti-Human P-Glycoprotein Antibody (DMAB5474MH)
Mouse anti-Human P-Glycoprotein Monoclonal antibody [clone G5] for IHC
Datasheet
Bring this labeled antibody directly to your bench!
Specifications
Host Species
Mouse
Antibody Isotype
IgG1
Clone
G5
Immunogen
Mixture of drug resistant human and hamster whole cells and crude plasma membranes.
Conjugate
Unconjugated
Product Background
Pathway
ABC transporters; ABC-family proteins mediated transport; Bile secretion; Codeine and morphine metabolism; HIF-1-alpha transcription factor network; Nuclear receptors in lipid metabolism and toxicity; Transmembrane transport of small molecules
Citations
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References
Glodkowska-Mrowka, E; Mrowka, P; et al. Statins inhibit ABCB1 and ABCG2 drug transporter activity in chronic myeloid leukemia cells and potentiate antileukemic effects of imatinib. EXPERIMENTAL HEMATOLOGY 42:439-447(2014).
Zhang, LN; Yesupriya, A; et al. Variants in ABCB1, TGFB1, and XRCC1 genes and susceptibility to viral hepatitis A infection in Mexican Americans. HEPATOLOGY 55:1008-1018(2012).
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Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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