Anti-Human P-Glycoprotein Antibody (DMAB5474MH)

Mouse anti-Human P-Glycoprotein Monoclonal antibody [clone G5] for IHC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
G5
Immunogen
Mixture of drug resistant human and hamster whole cells and crude plasma membranes.
Conjugate
Unconjugated

Target


Alternative Names
CLCS; MDR1; P-GP; PGY1; ABC20; CD243
Entrez Gene ID
UniProt ID

Product Background


Pathway
ABC transporters; ABC-family proteins mediated transport; Bile secretion; Codeine and morphine metabolism; HIF-1-alpha transcription factor network; Nuclear receptors in lipid metabolism and toxicity; Transmembrane transport of small molecules

Citations


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References


Joy, MS; Boyette, T; et al. Effects of uridine diphosphate glucuronosyltransferase 2B7 and 1A7 pharmacogenomics and patient clinical parameters on steady-state mycophenolic acid pharmacokinetics in glomerulonephritis. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY 66:1119-1130(2010).
Palmeira, A; Sousa, E; et al. Multidrug Resistance Reversal Effects of Aminated Thioxanthones and Interaction with Cytochrome P450 3A4. JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES 15:31-45(2012).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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