Anti-Human P-Glycoprotein Antibody (DMAB5474MH)
Mouse anti-Human P-Glycoprotein Monoclonal antibody [clone G5] for IHC
Datasheet
Specifications
Host Species
Mouse
Antibody Isotype
IgG1
Clone
G5
Immunogen
Mixture of drug resistant human and hamster whole cells and crude plasma membranes.
Conjugate
Unconjugated
Product Background
Pathway
ABC transporters; ABC-family proteins mediated transport; Bile secretion; Codeine and morphine metabolism; HIF-1-alpha transcription factor network; Nuclear receptors in lipid metabolism and toxicity; Transmembrane transport of small molecules
Citations
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References
van der Holt, B; Van den Heuvel-Eibrink, MM; et al. ABCB1 gene polymorphisms are not associated with treatment outcome in elderly acute myeloid leukemia patients. CLINICAL PHARMACOLOGY & THERAPEUTICS 80:427-439(2006).
Daood, M; Tsai, C; et al. ABC Transporter (P-gp/ABCB1, MRP1/ABCC1, BCRP/ABCG2) Expression in the Developing Human CNS. NEUROPEDIATRICS 39:211-218(2008).
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Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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