Anti-Human P-Glycoprotein Antibody (DMAB5474MH)

Mouse anti-Human P-Glycoprotein Monoclonal antibody [clone G5] for IHC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
G5
Immunogen
Mixture of drug resistant human and hamster whole cells and crude plasma membranes.
Conjugate
Unconjugated

Target


Alternative Names
CLCS; MDR1; P-GP; PGY1; ABC20; CD243
Entrez Gene ID
UniProt ID

Product Background


Pathway
ABC transporters; ABC-family proteins mediated transport; Bile secretion; Codeine and morphine metabolism; HIF-1-alpha transcription factor network; Nuclear receptors in lipid metabolism and toxicity; Transmembrane transport of small molecules

Citations


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References


van der Holt, B; Van den Heuvel-Eibrink, MM; et al. ABCB1 gene polymorphisms are not associated with treatment outcome in elderly acute myeloid leukemia patients. CLINICAL PHARMACOLOGY & THERAPEUTICS 80:427-439(2006).
Daood, M; Tsai, C; et al. ABC Transporter (P-gp/ABCB1, MRP1/ABCC1, BCRP/ABCG2) Expression in the Developing Human CNS. NEUROPEDIATRICS 39:211-218(2008).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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