Anti-Human P-Glycoprotein Antibody (DMAB5474MH)
Mouse anti-Human P-Glycoprotein Monoclonal antibody [clone G5] for IHC
Datasheet
Bring this labeled antibody directly to your bench!
Specifications
Host Species
Mouse
Antibody Isotype
IgG1
Clone
G5
Immunogen
Mixture of drug resistant human and hamster whole cells and crude plasma membranes.
Conjugate
Unconjugated
Product Background
Pathway
ABC transporters; ABC-family proteins mediated transport; Bile secretion; Codeine and morphine metabolism; HIF-1-alpha transcription factor network; Nuclear receptors in lipid metabolism and toxicity; Transmembrane transport of small molecules
Citations
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References
Daood, M; Tsai, C; et al. ABC Transporter (P-gp/ABCB1, MRP1/ABCC1, BCRP/ABCG2) Expression in the Developing Human CNS. NEUROPEDIATRICS 39:211-218(2008).
Kapoor, K; Bhatnagar, J; et al. Mutations in Intracellular Loops 1 and 3 Lead to Misfolding of Human P-glycoprotein (ABCB1) That Can Be Rescued by Cyclosporine A, Which Reduces Its Association with Chaperone Hsp70. JOURNAL OF BIOLOGICAL CHEMISTRY 288:32622-32636(2013).
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Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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