Synthetic Human AES blocking peptide for BL
Found predominantly in muscle, heart and Placenta. In fetal tissues, abundantly expressed in the heart, lung, kidney, brain and liver.
Belongs to the WD repeat Groucho/TLE family.
Lacks the C-terminal WD repeats.
Information available upon request.
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.
The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
protein binding; transcription corepressor activity; transcription corepressor activity;
AES; amino-terminal enhancer of split; GRG; ESP1; GRG5; TLE5; AES-1; AES-2; gp130-associated protein GAM;