Human AES blocking peptide (DAG-P1362)

Synthetic Human AES blocking peptide for BL Datasheet

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Found predominantly in muscle, heart and Placenta. In fetal tissues, abundantly expressed in the heart, lung, kidney, brain and liver.
Sequence Similarities
Belongs to the WD repeat Groucho/TLE family.
Cellular Localization
Alternative Names
Lacks the C-terminal WD repeats.
Information available upon request.
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.
UniProt ID
Antigen Description
The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
protein binding; transcription corepressor activity; transcription corepressor activity;
AES; amino-terminal enhancer of split; GRG; ESP1; GRG5; TLE5; AES-1; AES-2; gp130-associated protein GAM;


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