Human SEPT4 blocking peptide

Nature

Synthetic

Tag/Conjugate

Unconjugated

SequenceSimilarities

SEPT4 peptide is a synthetic peptide corresponding to the internal region of SEPT4 (aa425-435).

Purity

> 95 % by SDS-PAGE.

Format

Lyophilized

Preservative

None

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. PBS with 0.1% BSA 0.02% sodium azide pH7.2

Reconstitution

SEPT4 peptide is supplied as 1mg of dried peptide. When the peptide is reconstituted in 1 mL strile water, the concentration will be 1 mg/mL.

Introduction

This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer. [provided by RefSeq, Nov 2010]

Entrez Gene ID

Synonyms

SEPT4; septin 4; H5; ARTS; MART; SEP4; CE5B3; PNUTL2; hucep-7; BRADEION; hCDCREL-2; septin-4; septin-M; CE5B3 beta; bradeion beta; brain protein H5; cerebral protein 7; peanut-like protein 2; cell division control-related protein 2; apoptosis-related protein in the TGF-beta signaling pathway;