Specificity
Detected in heart, liver, lung and liver (at protein level). Detected in fetal heart, lung, liver and kidney. Detected in adult heart, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Tag/Conjugate
Unconjugated
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.
Antigen Description
The protein encoded by this gene belongs to the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally related to ADP-ribosylation factors (ARFs). ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity, regulate intracellular vesicular membrane trafficking, and stimulate a phospholipase D (PLD) isoform. Although, ARL proteins were initially thought not to activate CT or PLD, later work showed that they are weak stimulators of PLD and CT in a phospholipid dependent manner. [provided by RefSeq, Jul 2008]
Function
GTP binding; GTPase activity; enzyme activator activity; metal ion binding; protein domain specific binding;
Synonyms
ARL1; ADP-ribosylation factor-like 1; ARFL1; ADP-ribosylation factor-like protein 1;
Citations
Have you cited DAG-P1389 in a publication?
Let us know and earn a reward for your research.
| Product Name |
Cat. No. |
Applications |
Host Species |
Datasheet |
Price |
Add to Basket |
| Product Name |
Cat. No. |
Applications |
Host Species |
Datasheet |
Price |
Add to Basket |
Lowe, SL; Wong, SH; et al. The mammalian ARF-like protein 1 (ArI1) is associated with the Golgi complex. JOURNAL OF CELL SCIENCE 109:209-220(1996).
Lee, FJS; Huang, CF; et al. Characterization of an ADP-ribosylation factor-like 1 protein in Saccharomyces cerevisiae. JOURNAL OF BIOLOGICAL CHEMISTRY 272:30998-31005(1997).