Product Overview
Blocking/Immunizing peptide for anti-ARH/LDL receptor adaptor antibody
Target
ARH / LDL receptor adaptor
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
The protein encoded by this gene is a cytosolic protein which contains a phosphotyrosine binding (PTD) domain. The PTD domain has been found to interact with the cytoplasmic tail of the LDL receptor. Mutations in this gene lead to LDL receptor malfunction and cause the disorder autosomal recessive hypercholesterolaemia. [provided by RefSeq, Jul 2008]
Function
AP-2 adaptor complex binding; beta-amyloid binding; clathrin adaptor activity; clathrin binding; low-density lipoprotein particle receptor binding; phosphatidylinositol-4,5-bisphosphate binding; phosphotyrosine binding; protein binding; receptor signaling
Synonyms
LDLRAP1; low density lipoprotein receptor adaptor protein 1; ARH; ARH1; ARH2; FHCB1; FHCB2; low density lipoprotein receptor adapter protein 1; LDL receptor adaptor protein; autosomal recessive hypercholesterolemia protein;
Citations
Publication ()
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COA
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