Human GFER peptide

Specificity

Ubiquitously expressed. Highest expression in the testis and liver and low expression in the muscle.

Nature

Synthetic

Tag/Conjugate

Unconjugated

SequenceSimilarities

Contains 1 ERV/ALR sulfhydryl oxidase domain.

Format

Liquid

Preservative

None

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.

Entrez Gene ID

Antigen Description

The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver. It has also been called hepatic regenerative stimulation substance (HSS). The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1). The putative gene product is 42% similar to the scERV1 protein of yeast. The yeast scERV1 gene had been found to be essential for oxidative phosphorylation, the maintenance of mitochondrial genomes, and the cell division cycle. The human gene is both the structural and functional homolog of the yeast scERV1 gene. [provided by RefSeq, Jul 2008]

Function

flavin adenine dinucleotide binding; growth factor activity; protein binding; protein disulfide oxidoreductase activity; thiol oxidase activity;

Synonyms

GFER; growth factor, augmenter of liver regeneration; ALR; HPO; HSS; ERV1; HPO1; HPO2; HERV1; FAD-linked sulfhydryl oxidase ALR; ERV1 homolog; hepatopoietin protein; erv1-like growth factor; hepatic regenerative stimulation substance;