Product Overview
Blocking/Immunizing peptide for anti-ALDH3B2 antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
This gene encodes a member of the aldehyde dehydrogenase family, a group of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The gene of this particular family member is over 10 kb in length. The expression of these transcripts is restricted to the salivary gland among the human tissues examined. Alternate transcriptional splice variants have been characterized.
Function
3-chloroallyl aldehyde dehydrogenase activity; aldehyde dehydrogenase [NAD(P)+] activity; oxidoreductase activity;
Synonyms
ALDH3B2; aldehyde dehydrogenase 3 family, member B2; ALDH8; aldehyde dehydrogenase family 3 member B2; acetaldehyde dehydrogenase 8; aldehyde dehydrogenase 8;
Citations
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Holmes, RS; Hempel, J; et al. Comparative studies of vertebrate aldehyde dehydrogenase 3: Sequences, structures, phylogeny and evolution. Evidence for a mammalian origin for the ALDH3A1 gene. CHEMICO-BIOLOGICAL INTERACTIONS 191:113-121(2011).
Zhang, RL; Miao, Q; et al. Genome-wide DNA methylation analysis in alcohol dependence. ADDICTION BIOLOGY 18:392-403(2013).