Anti-AKR1C4 monoclonal antibody (DMABT-H13017)

Mouse anti-Human AKR1C4 monoclonal antibody for WB, IHC, IF, sELISA, ELISA Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
3D22
Species Reactivity
Human
Immunogen
AKR1C4 (AAH20744,2a.a. ~ 323 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated

Target


Alternative Names
AKR1C4; aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4); CHDR; aldo-keto reductase family2member C4
Entrez Gene ID
UniProt ID

Product Background


Pathway
Bile acid and bile salt metabolism, organism-specific biosystem; Bile acid biosynthesis, cholesterol =>cholate, organism-specific biosystem; Bile acid biosynthesis, cholesterol =>cholate, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem;

Citations


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References


O'Connor, T; Ireland, LS; et al. Major differences exist in the function and tissue-specific expression of human aflatoxin B-1 aldehyde reductase and the principal human aldo-keto reductase AKR1 family members. BIOCHEMICAL JOURNAL 343:487-504(1999).
Ozeki, T; Takahashi, Y; et al. Hepatocyte nuclear factor (HNF)-4 alpha/gamma, HNF-l alpha, and vHNF-1 regulate the cell-specific expression of the human dihydrodiol dehydrogenase (DD),4/AKR1C4 gene. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 405:185-190(2002).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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