Human AIRE blocking peptide (CDBP0353)

Synthetic Human AIRE blocking peptide for Apuri, BL, ELISA Datasheet

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Product Overview
Blocking/Immunizing peptide for anti-AIRE (isoforms 1 and 2) antibody
AIRE (isoforms 1 and 2)
Species Reactivity
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Lyophilized powder
100 μg
Shipped at ambient temperature, store at -20°C.
UniProt ID
Antigen Description
This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).
DNA binding; chromatin binding; histone binding; identical protein binding; metal ion binding; protein binding; transcription regulatory region DNA binding; translation regulator activity; zinc ion binding;
AIRE; autoimmune regulator; APECED, autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy); APS1; autoimmune polyendocrinopathy candidiasis ectodermal dystrophy; PGA1; autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein; APSI; AIRE1; APECED;


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