AGR2 (anterior gradient 2) is a protein-coding gene. Diseases associated with AGR2 include dubowitz syndrome, and coccidioidomycosis. GO annotations related to this gene include dystroglycan binding and protein binding. An important paralog of this gene is TXNDC12. Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth.
Function
alpha-dystroglycan binding; protein binding;
Synonyms
AGR2; anterior gradient 2 homolog (Xenopus laevis); anterior gradient protein 2 homolog; AG2; HAG 2; PDIA17; protein disulfide isomerase family A; member 17; XAG 2; AG-2; HPC8; anterior gradient homolog 2; secreted cement gland homolog; secreted cement gland protein XAG-2 homolog; protein disulfide isomerase family A, member 17; GOB-4; HAG-2; XAG-2;
Citations
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