Application Notes
Suitable for use in Control, ELISA.
Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
General Notes
This product (Catalog No. DMAB-CBXY26008) is a human-derived monoclonal antibody raised against yfv YFV Env. It has been affinity purified by Protein A. Yellow fever virus (YFV) is an RNA virus that belongs to the genus Flavivirus. Over 100 species comprise the genus Flavivirus, which includes other notable human pathogens, such as dengue virus (DENV), Japanese encephalitis virus (JEV), Zika virus (ZIKV), West Nile virus (WNV), Kyasanur Forest disease virus, and tick-borne encephalitis virus. Mature YFV virion is an icosahedral particle about 40 nm in diameter. Like other flaviviruses, YFV contains a small glycoprotein-containing lipid envelope surrounding a nucleocapsid which encloses one viral RNA. The envelope of the virus is inlaid with two virally encoded proteins: envelope (E) protein and membrane (M) protein. The E glycoprotein is the major component of the virion surface and is responsible for the receptor-mediated endocytic fusion and subsequent cell entry, as well as direct viral assembly ＆ budding, and immunogenicity.
DMAB-CBXY26008 is suitable for use in Suitable for use in Control, ELISA applications.
DMAB-CBXY26008 is supplied as a liquid formulation in PBS-Tris. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
COA
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