Mouse anti-UBE2W monoclonal antibody (CABT-B11730)

Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
8H5
Species Reactivity
Human
Immunogen
UBE2W (NP_001001481, 17 a.a. ~ 113 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated

Target


Alternative Names
ubiquitin-conjugating enzyme E2W (putative); EC 6.3.2.19; FLJ11011; hUBC-16; Ubiquitin carrier protein W; probable ubiquitin-conjugating enzyme E2 W
Entrez Gene ID
UniProt ID

Product Background


Pathway
Adaptive Immunity Signaling, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem; Ubiquitin mediated proteolysis, organism-specific biosystem; Ubiquitin mediated proteolysis, conserved biosystem

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Christensen, DE; Brzovic, PS; et al. E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages. NATURE STRUCTURAL & MOLECULAR BIOLOGY 14:941-948(2007).
Scaglione, KM; Basrur, V; et al. The Ubiquitin-conjugating Enzyme (E2) Ube2w Ubiquitinates the N Terminus of Substrates. JOURNAL OF BIOLOGICAL CHEMISTRY 288:18784-18788(2013).

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